Online monitoring of glucose
BioPAT® Trace is used in laboratories for simultaneous online monitoring of glucose and lactate, e.g. for industrial cultivation of microorganisms or mammalian cells.
The BioPAT® Trace provides continuous online process analysis regardless of the cultivation type (batch/fed-batch). The BioPAT® Trace can provide online analysis of up to 4 bioreactors simultaneously.
The BioPAT ® Trace has three sampling options available: filtration probe, dialysis probe and bypass block. These options all enable sterile removal from the bioreactor.
Online monitoring of glucose/lactate means:
- 24/7 monitoring of the process
- Short response time
- Control based on measurements ensures a stable glucose level (50mg/l - 2g/l) in the medium
- Possible to check conditions for optimum cultivation
There are two different sensors. A filter probe, where the sample is taken out and analyzed in the apparatus, and a dialysis probe for direct measurement of the glucose/lactate concentration. The probes are available for 12 mm, 19 mm and 25 mm ports. Both types are of course suitable for sterile sampling.
The analysis functions in the BioPAT® Trace are based on a combination of enzymatic reactions and anode oxidation on which glucose and lactate concentrations can be detected as function of the conductivity.
Datasheet BioPAT® Trace and BioPAT® Multi Trace